IV Ketamine Therapy

• • Treatments • •

IV Ketamine Therapy in Southern California

At Neuro Wellness Spa, we are proud to be one of the leading providers of intravenous (IV) ketamine therapy in Los Angeles, California.

Although ketamine has been used safely as an FDA-approved anesthetic since the 1960s, the discovery of ketamine as a highly effective and rapid-acting treatment for a wide range of mood disorders and neuropathic pain has been hailed as arguably the most significant development in psychiatry during the past few decades.

What is IV Ketamine Therapy?

A Breakthrough Medicine of the Mind

Ketamine can rapidly—often within an hour or two—lift the symptoms of anxiety, depression, PTSD, OCD, and other conditions. After a short series of repeated doses, this effect typically extends out for weeks to months.

Ketamine is an FDA-approved anesthetic that is used off-label to treat mood, anxiety and pain. During each infusion, patients experience deep relaxation and typically wear an eye mask in a dimly lit room with aromatherapy.

At Neuro Wellness Spa, our thoughtfully designed treatment centers ensure a safe, comfortable and private experience while our therapeutic processing and integration enhance ketamine’s direct effects on the brain and psyche resulting in profound emotional insights and deep inner healing.

The Neuroscience of Ketamine

In the cerebral cortex alone, the most highly developed part of the brain, there are somewhere between 14 and 16 billion neurons. Neurons communicate with each other via neurotransmitters: chemicals that act as messengers between neurons.

Different neurotransmitters affect neurons in different ways. Glutamate is the most common excitatory neurotransmitter in the brain. It plays a particularly important role in neuroplasticity (the brain’s ability to form new synapses and neural connections over a lifetime), learning, and forming memories.

Ketamine is an NMDA receptor antagonist that interacts with glutamate. Research shows ketamine increases the expression of Brain-Derived Neurotrophic Factor (BDNF). This results in enhanced neuroplasticity, or the ability of brain cells to form new connections with one another.

In patients treated with IV ketamine therapy, researchers have observed increased synaptic connections. This neuronal growth and increased neuronal interconnectivity have been shown to improve mood and cognition in as little as one hour.

What Can IV Ketamine Therapy Treat?

Millions of people struggle with psychiatric disorders, including anxiety, depression, and PTSD, and with chronic pain. Many of these conditions may be treatment refractory, not responding to antidepressants or other therapies. IV ketamine therapy is a safe and effective treatment option, especially for those who have not experienced satisfactory symptom relief from medications and talk therapy, for:

  • Depression
  • Anxiety
  • Acute suicidality
  • PTSD
  • Chronic pain

Ketamine has the ability to go to work rapidly. Symptoms tend to improve within just hours after the first infusion compared to the 6–12 week onset period of conventional medications. Ketamine has been shown to help relieve symptoms of disorders including:

Bipolar Disorder

Bipolar disorder causes alternating feelings of depression and elation. IV ketamine therapy can help balance cerebral activity, and may alleviate some of the symptoms of bipolar disorder.

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Ketamine is effective in treating various chronic pain syndromes, especially those that have a neuropathic component, like fibromyalgia.

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Anxiety disorder is highly prevalent in the United States. According to the Anxiety and Depression Association of America, it affects about 40 million Americans, which is approximately 20% of the population. Ketamine therapy plays an important role in the treatment of anxiety. Approximately 30-40% of those seeking treatment for anxiety, do not achieve remission with standard medications and therapies. IV ketamine has been proven to effectively treat anxiety in patients with treatment-resistance.

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Chronic Pain

Ketamine is a powerful pain reliever. It has been used as an anesthetic during surgery. Ketamine is safe, especially compared to other anesthetics, because it offers fast-acting pain relief without causing respiratory suppression. There is growing evidence that treatment of chronic pain with ketamine provides prolonged pain relief.

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Spinal Injury

Ketamine can relieve pain caused by spinal cord injuries. Ketamine works by stimulating brain derived neurotrophic factor (BDNF) and the growth of neurons in the brain. Researchers have also observed increased synaptic connections in patients treated with IV ketamine therapy. This neuronal growth and increased neuronal interconnectivity relieve symptoms of spinal injuries.

Post Traumatic Stress Disorder

More than 3 million US adults suffer from PTSD each year. It is highly prevalent among military personnel, victims of domestic violence, and those who have suffered an accident or another type of traumatic event. IV ketamine has been shown to relieve symptoms of PTSD.

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The National Institute of Mental Health lists depression as one of the most common mental illnesses in the United States. In a recent study, around 17 million adults in the US had at least one major depressive episode in the past year.

However, standard antidepressant and therapy treatments do not work for everyone with depression. IV ketamine therapy is a well-established, safe and effective treatment option for those with treatment-resistant depression.

Phantom Limb Pain

Although there is still a lot unknown about phantom limb pain, it is clear that PLP involves both central and peripheral neural factors that activate N-methyl-D-aspartate (NMDA) receptors. Ketamine is known to block these NMDA receptors. Because of this, IV ketamine is considered to be a potentially effective treatment for many neuropathic disorders, including PLP.

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Neuralgia is a mild to severe, shooting pain felt along a nerve pathway. Although are different types of neuralgia, they all can affect the ability to perform everyday tasks and can reduce quality of life. If medications and nonpharmacological interventions don’t work, IV ketamine therapy may be a treatment option for neuralgia. IV ketamine is known for its ability to help relieve therapy-resistant chronic pain syndromes, especially those syndromes that have a neuropathic component, including neuralgia.

Your Brain and Ketamine, Why It Works.

Ketamine’s response rate is more than double that of traditional antidepressants and ketamine works rapidly, in hours to days, compared to antidepressants which take weeks to exert their full effects.

For most patients, ketamine also has transformative effects on an individual’s worldview. Ketamine produces a sense of disconnection from one’s ordinary reality and usual self that may induce or enhance feelings of creativity, purpose, perspective, serenity, insight, inspiration, gratitude, empathy, connection with others and the world, openness to new ideas, psychological rebirth, and traveling outside of one’s self, among others.

Following treatment, patients report beneficial shifts in awareness or perspective and identify more strongly with positive self-images and values and often describe a newfound sense of meaning or purpose. IV ketamine therapy has also been found to increase compassion, reduce fear of death, and increase joy in living.

But how?

Ketamine works in several ways at the same time. Research into the full pharmacological action of ketamine is revealing just how complex the response to this drug is.

Ketamine is an NMDA receptor antagonist that stimulates brain derived neurotrophic factor (BDNF). Additionally, ketamine activates the limbic system (associated with memory, emotion, and behavior) and strengthens the interaction between the conscious and subconscious levels of the mind.

In patients treated with IV ketamine therapy, researchers have observed increased synaptic connections and the growth of neurons.  This neuronal growth and increased neuronal interconnectivity improve mood and cognition and allow patients to disengage from their routine thought patterns, heal unhealthy neural pathways and achieve clarity.

Experts on Ketamine In the News

Extensive research and highly-effective treatment outcomes have greatly contributed to several notable publications about ketamine therapy, with more being published every day:

  • NPR Ketamine for Severe Depression, ‘How Do You Not Offer This Drug To People? 3 Minute Listen.
  • NPR From Chaos to Calm: A Life Changed by Ketamine. 6 Minute Listen.
  • BBC News Ketamine Has ‘Fast-Acting’ Benefits for Depression. Read More.
  • New York Times Johns Hopkins Opens New Center for Psychedelic Research. Read More.
  • New York Times Fast Acting Depression Drug, Newly Approved, Could Help Millions. Read More.
  • NIMH New Hope for Treatment Resistant Depression: Guessing Right on Ketamine. Read More.
  • Washington Post One Time Party Drug Hailed As Miracle for Treating Severe Depression. Read More.
  • TIME New hope for depression. Read More.
  • Bloomberg How ketamine opens a new era for depression treatment. Read More. 
  • Forbes Ketamine may reduce depression, suicidal thoughts within hours. Read More.
  • Psychiatry Advisor Ketamine: a promising novel therapy for anxiety and PTSD. Read More. 
  • PsyPost Ketamine may ease depression by restoring the brain’s sensitivity to prediction error, study suggests. Read More.

Contact us today to learn more about IV ketamine or to schedule a no cost consultation. Get started today.

The Ketamine Treatment Process:

At Neuro Wellness Spa, our ketamine protocol supports each patient’s unique needs and journey. Our thoughtfully designed treatment centers ensure a safe, comfortable and private experience while our therapeutic processing and integration enhance ketamine’s direct effects on the brain and psyche resulting in profound emotional insights and deep inner healing. Our team is always available to discuss and answer any questions you may have.

Free Consultation

You may be feeling lonely, disconnected, or lost – all of which can be signs of depression or past trauma. No matter what you are going through, we believe in every person’s ability to heal.

During the consultation, one of our world-class psychiatrists will review your medical records, discuss your needs and preferences, answer any questions you may have and help you decide whether IV ketamine therapy may be an effective treatment for you.


Neuro Wellness Spa’s treatment programs are guided by scientific research and the wisdom of traditional practices. Each treatment program combines the use of ketamine with therapeutic preparation and integration.

During the preparation session, one of our providers will help you set goals for your experience and establish an intention that will shape your integration work. The stronger and clearer the intention, the more profound the transformation can be.


Each ketamine infusion lasts about 40 minutes, after which patients should have someone available to accompany them home safely. During the infusion, patients experience deep relaxation and typically wear an eye mask in a dimly lit room with aromatherapy.

Ketamine is delivered at a slow and controlled dose and a registered nurse is present for the duration of the infusion. Blood pressure, heart rate and oxygen saturation are monitored.

Typically, patients receive a course of 6-12 ketamine infusions over 2-4 weeks. The frequency and number of sessions are individualized. Most patients experience positive results from ketamine after their first infusion. Subsequent infusions help prolong the positive effects.


In each integration session, you will work with a provider to derive meaning from your IV ketamine therapy experience, and translate that awareness into tangible everyday life practices. Integration work takes the ketamine experience and turns it into sustainable, impactful change.


Is IV Ketamine Therapy Covered by Insurance?

Although IV ketamine is FDA-approved as an anesthetic, it is used off-label to treat mood and chronic pain disorders. At the present time, ketamine infusions for mood and chronic pain disorders are cash pay procedures.

We recognize that there are financial considerations to take into account when starting treatment. Our team is always available to discuss and answer any questions you may have about your payment options.

We accept insurance from the following providers

• • Testimonials • •

You Are Not Alone

Here’s What Our Patients Are Saying

  • It’s Almost Indescribable

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    It felt like a weight or a fog had lifted. Every area of my life turned around. I feel better, my sleep and my relationships are better. It’s almost indescribable.

  • TMS Changed Everything

    star star star star star

    I was so low energy and TMS changed everything. Now, I look forward to starting my days. My focus has improved. I appreciate things I couldn’t even notice before

  • Wish I Had Been Aware of This Years Ago

    star star star star star

    After about ten treatments, people started asking me what changed and why I seemed so much happier. It’s been over 3 months since my treatments ended and my symptoms have not returned.

  • I Feel Like I Have Come Alive Again

    star star star star star

    TMS allowed me to get over the initial hump to make the life changes necessary to live with and manage my depression.

  • My Brain Is In A Better Place

    star star star star star

    I’m two or three months past my last MeRT treatment, and I can honestly say my brain is in a better place than it was before. The emotional highs and lows I was living with have been stabilized. My cognition took off during that period and it hasn’t slowed down since.

    N.H., Retired NFL Player
  • He’s Been More Talkative and Engaged

    star star star star star

    After just two weeks of MeRT treatment, our son’s mood is brighter. He’s been more talkative and engaged with our family.

    MeRT Patient
  • The MeRT Technology Saved My Life

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    I went from dependence on opioids, SSRI’s, Benzes and sleep meds to clear in less than 6 weeks. The MeRT technology saved my life.

    J.S., SEAL Team 6
  • We Got Our Son Back

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    After eight weeks of MeRT treatments, he’s now much more verbal and much happier. He started communicating with us and making jokes. And he has a love of music we didn’t even know about. We got our son back.

    MeRT Patient
  • Ketamine Therapy Changed My Life

    star star star star star

    My life has completely changed. I experienced so much growth during the entire treatment process. I think I grew more in those six months than I had during my entire life. My therapist even said she had never seen such incredible progress with my PTSD in such a short amount of time.


For more information about the services we offer or whether TMS treatment is covered by your insurance provider, contact us today.

• • Get in touch • •

Contact Us

    Could TMS Therapy Be Right For You?

    I struggle with depression, OCD or anxiety.

    I am experiencing sadness, low energy, difficulty sleeping, poort concentration, appetite changes, irritability or weight gain/loss.

    I have tried, or am currently on, 3 or more antidepressant medications

    I have tried talk therapy

    Has your doctor/therapist suggested you try TMS?

    Call Us Today

    Call Us Today