• • Ketamine Therapy • •

Ketamine Treatment for Bipolar Disorder in Southern California

Intravenous (IV) ketamine therapy delivers ketamine, an FDA- approved anesthetic, through an IV to improve a patient’s neural activity and neural connectivity. IV ketamine has been shown to be an effective treatment for a variety of psychiatric disorders, particularly treatment-resistant depression, anxiety and bipolar disorder.

What is Ketamine IV Therapy?

Millions of people suffer from chronic and debilitating physical and psychiatric disorders, including anxiety and depression. However, many of these conditions may stop responding to medications, like anti-depressants, and other therapies. IV ketamine therapy is a safe and effective treatment option for people who suffer from treatment-resistant:

  • Depression
  • Anxiety
  • Acute suicidality
  • PTSD
  • Chronic pain

Physicians have used Ketamine for over 50 years as an anesthetic. However, new research indicates its effectiveness in other applications too.

Researchers at Mass General Hospital conducted the largest study of IV ketamine therapy. They found that over 70% of patients suffering from treatment-resistant depression experienced symptom relief with IV ketamine therapy. This study, along with a growing number of others, is a major finding that demonstrates the effectiveness of IV ketamine for those who have tried standard treatments but haven’t responded adequately.

How Is Bipolar Disorder Treated with IV Ketamine Therapy?

IV Ketamine therapy produces proteins that increases neuronal connectivity and repairs neural connections. This process is known as synaptic plasticity. As synaptic connections are strengthened, our brains are better able to combat stress and depression.

During a ketamine infusion, patients experience the feeling of dissociation. One benefit of dissociating is that it allows the patient to experience the present and past as an objective observer, removed from psychological stress. Also, while receiving treatment, many patients enter a state of deep relaxation as their minds wander without worry.

At Neuro Wellness Spa, our trained clinicians supervise all ketamine treatments. One ketamine infusion lasts approximately 40 minutes during which ketamine is dosed based on the patient’s body weight (0.5mg/kg). The typical course of treatment includes 8-12 infusions over the course of 3-4 weeks.

The drug is administered at a slow and controlled pace to the patient by a trained clinician. Patients do not experience any cardiovascular, respiratory, or hallucinogenic effects during or after the treatment.

In fact, IV Ketamine doesn’t have any long-lasting associated side effects. Although some people may experience sensitivity to light and/or sound and disorientation while the treatment is administered, these feelings subside quickly when the treatment is finished.

Anhedonia is what inhibits people with bipolar disorder from feeling or seeking pleasure. It may take traditional antidepressants weeks or even months to treat this symptom. However, IV ketamine is able to reverse anhedonia, and most patients who have had IV ketamine feel a significant improvement after the first treatment session. This improvement wanes over the subsequent 24-48 hours, but as the IV ketamine protocol continues, the symptom relief becomes increasingly sustained.

What Is Bipolar Disorder?

Bipolar disorder was previously known as manic depression. Bipolar disorder causes extreme mood swings,  including both emotional lows (depression) and highs (mania).

There are different types of bipolar disorder:

  • Bipolar 1 disorder: at least one manic incident that may be followed or preceded by major depressive or hypomanic episodes
  • Bipolar 2 disorder: at least one hypomanic episode and one major depressive episode but never a manic episode
  • Cyclothymic disorder: at least two years of multiple periods of depressive and hypomanic symptoms never meeting full criteria for major depression or hypomania

Those who suffer with bipolar disorder may be reluctant to seek out treatment. They may enjoy the feelings of euphoria as well as the increased productivity of hypomanic/manic episodes. However, euphoria may lead to impulsivity or risky behaviors which are often followed by a crash that can leave the patient in a depressed state.


Bipolar Statistics

Approximately 2.8% of the United States population is diagnosed with bipolar disorder. The disorder affects men and women equally. Of the people affected, 83% have been classified as severe cases of bipolar disorder.

If standard medications and nonpharmacological interventions don’t work in a patient with bipolar disorder, IV ketamine therapy may be a treatment option. IV ketamine is known for its ability to help relieve therapy-resistant bipolar disorder. Ketamine is “helpful for patients that have exhausted other therapeutic options,” according to The National Center for Biotechnology Information.

Signs & Symptoms of Bipolar Disorder

A person with bipolar disorder may experience a major depressive episode, mania, or hypomania. A major depressive episode would include symptoms that are severe enough to make day-to-day activities noticeably difficult. This can impact one’s social activities, school, work, and relationships.

A depressive episode may include symptoms such as:

  • Depressed mood
  • Loss of interest or pleasure in all or almost all activities
  • Fatigue
  • Suicidal thoughts
  • Sleeping too much or insomnia
  • Feelings of worthlessness

Mania is more intense than hypomania. And although the two are distinct types of episodes, they have the same symptoms. Like depressive episodes, mania causes noticeable problems in daily activities. Both hypomanic and manic episodes may include increased energy. They may also include:

  • Racing thoughts
  • Impulsive decision making
  • Unusual talkativeness
  • Euphoria or irritability
  • Decreased need for sleep

If you or a loved one is experiencing symptoms of mania or depression, talk to your doctor or a mental health professional. It is important to recognize that bipolar disorder does not get better without treatment.

How Does This Therapy Feel?

At Neuro Wellness Spa, we administer low levels of ketamine in a controlled environment.

Ketamine can be used an anesthetic during surgery. However, the dosage we use during therapy is much lower.

At Neuro Wellness Spa we use FDA-approved doses and closely monitor our patients to make sure they are comfortable and relaxed.

What can I expect during IV Ketamine Therapy Treatments

One-on-One Consultation with an Expert Psychiatrist

A physician will begin by reviewing your medical records and consulting with you about your needs and preferences for treatment.

You will be asked some important questions.

Such as height, weight, age, and medical history as part of your treatment assessment. This information helps the physicians and medical staff prepare your treatment plan.


Ketamine infusions are administered on an outpatient basis.

Ketamine is administered through an IV, and the infusion lasts between 40-50 minutes.

Your treatment environment can have a large impact on your experience of the infusion.

Your clinician may lower the lights, offer an eye mask or aromatherapy, or take other measures to make the setting more comfortable. You might also choose some relaxing music to help you through the onset phase.

Ketamine is administered through an IV.

You will receive treatment in a private room, accompanied by a trained healthcare professional for the duration of the infusion. As the ketamine is delivered at a low and controlled dosage, your blood pressure, pulse and oxygen saturation will be monitored.

IV Ketamine therapy is fast-acting.

Although you remain aware of your surroundings, you will experience deep relaxation. It is important to enter each infusion with a positive mindset and a tranquil setting.

Some patients may experience dizziness, nausea, dissociation or fatigue.

A complete list of possible side effects will be discussed with you prior to treatment. After a treatment session, it is important to have someone available to accompany you home safely.

Your mindset and emotional state before treatment can impact your experience of the infusion.

Prior to every ketamine infusion, we help our patients prepare intentions for their therapy. The stronger and clearer the intention, the more profound it may help the therapy to be.

Contact Neuro Wellness Spa

If  you are interested in learning more about  IV ketamine therapy, or would like to speak with one of our experienced psychiatrists, please call us at 1-877-847-3984 or send us a message to schedule a free consultation.

For more information about the services we offer or whether TMS treatment is covered by your insurance provider, contact us today.

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