Dopamine detox is a concept that has gained momentum in recent years. It’s a process that describes taking a break from activities that release dopamine like social media, video games, recreational drugs, or other compulsive behaviors that invoke a dopamine response to activate our brain’s reward system.

All About Dopamine

Dopamine is a specific type of monoamine neurotransmitter that is found naturally in the brain. It functions in several ways, such as a chemical messenger, transmitting messages between nerve cells within your brain and the rest of the body. Dopamine plays many critical roles, such as:

• Initiating actions
• Controlling movement 
• Regulating emotion and behavior
• Motivation
• Facilitating learning
• Sleep and arousal
• Attention 
• Memory
• Lactation

Naturally occurring dopamine is important for many bodily functions. It can act as a vasodilator in small doses, causing blood vessels to relax, or work as a vasoconstrictor in large amounts, causing blood vessels to constrict.

Dopamine also functions as a hormone (catecholamines), produced by the adrenal gland (a small gland located at the top of each kidney), and releases dopamine into the bloodstream. Dopamine is involved in the body’s “fight or flight” response. This refers to the body’s ability to respond to real or perceived threats, like fleeing danger.

Dopamine enhances sodium elimination (salt and urine) from the body. It decreases insulin production in the pancreas, slows GI content movement, protects the GI lining, and reduces lymphocyte activity in the immune system. Dopamine also functions as a neurohormone; the hypothalamus in your brain also releases dopamine. It is the “feel-good” hormone because it is responsible for feeling happy or experiencing pleasure. It is part of the brain’s reward system, which plays a role in human evolution. It rewards people for doing things needed for survival, like eating, drinking, and reproducing. 

The human brain naturally pursues activities that activate dopamine release in our reward center. Engaging in pleasurable actions triggers a dopamine surge in the brain’s reward pathways. This leads to happiness and a desire for more of that enjoyable experience. This explains the addictive nature of junk food and sugar, as they stimulate the brain to release a substantial amount of dopamine, creating a pleasurable sensation and reinforcing addictive behaviors.

When we have the right balance of dopamine, we feel alert, focused, motivated, and happy. However, when the levels are lower, we may feel unhappy, unmotivated, and tired and experience mood swings or trouble remembering things. People experiencing high amounts of dopamine might experience increased energy, euphoria, and sexual drive but may have problems with aggression, controlling impulses, or sleeping.

What is Dopamine Detox?

Dopamine detox, also known as dopamine fasting, has gained popularity in recent years, particularly in fast-paced, high-stimulation environments like Silicon Valley. Despite its name, it’s essential to understand that you can’t actually “detox” or “fast” from dopamine, as it’s a naturally occurring neurotransmitter essential for many bodily functions.

The Concept

The idea behind dopamine detox is to take a break from activities that trigger high levels of dopamine release in the brain. These activities might include:

• Social media use
• Video gaming
• Recreational drug use
• Excessive internet browsing
• Compulsive shopping
• Binge-eating, especially of sugary or junk foods
• Thrill-seeking behaviors
• Excessive porn consumption or masturbation

The goal is to reset our sensitivity to dopamine and break cycles of addictive or compulsive behaviors.

Origins and Misconceptions

The term “dopamine fasting” was first introduced by Dr. Cameron Sepah, a psychiatrist and professor at UCSF Medical School. However, it’s crucial to note that his original concept has often been misinterpreted or taken to extremes in popular media.

Contrary to some interpretations, dopamine detox doesn’t involve trying to eliminate dopamine from your system. Instead, it’s about managing behaviors that may lead to unhealthy dopamine spikes and creating a more balanced relationship with rewarding activities.

The Science Behind It

While the term “detox” isn’t scientifically accurate in this context, the principle behind dopamine detox is rooted in established psychological concepts:

1. Stimulus Control: This involves managing external triggers that lead to compulsive behaviors.
2. Behavioral Addiction: Recognizing that certain behaviors can become addictive due to their effects on the brain’s reward system.
3. Hedonic Adaptation: The idea that we get used to pleasurable stimuli over time, requiring more stimulation to get the same effect.

Dopamine Detox Misconceptions

As we learned earlier, dopamine is a neurotransmitter within the human body, playing a crucial role in various functions such as reward, motivation, learning, and pleasure.

Although dopamine levels increase in response to rewarding experiences or pleasurable activities, it is essential to note that they do not decrease when one consciously avoids overstimulation. Therefore, partaking in a so-called “dopamine detoxes” does not actually reduce dopamine levels.

Dopamine fasting and dopamine detox do not result in decreasing dopamine levels. Instead, the essence of dopamine fasting and detox lies in restraining impulsive behaviors amplified by dopamine effects. In essence, it’s not the dopamine itself that is being “fasted” from, but rather the impulsive tendencies that dopamine-fueled behaviors can foster.

Our society is full of things designed to give our bodies a hit of dopamine, and mental health around the nation suffers for that reason. Responding to recurring external stimuli, such as constant notifications on a smartphone, can become conditioned signals just as addictive as novelty-seeking recreational drugs. Dr. Sepah explains that these conditioned signals teach us to anticipate a reward and encompass negative reinforcement (relieving negative emotions) or positive reinforcement (encountering something new).

Sepah explains that this “double reinforcement” process can contribute to impulsive or addictive actions. Feelings such as boredom, anxiety, anger, sadness, or loneliness prompt the pursuit of these cutes to relieve negative emotions and offer enjoyable diversions.

Benefits of Dopamine Detox

So, while no silver bullet will instantly solve many of life’s problems or cure addiction, several “dopamine detoxing” practices can benefit our mental health and guide us toward healthier habits. First, it provides insights into human behavior and addiction. 

By understanding the role that dopamine plays in pleasure-seeking and reward-seeking behavior, people can make informed decisions about their lifestyle choices and develop more effective strategies for managing their dopamine levels, such as limiting screen time, social media use, and eating processed foods and implementing healthy activities such as prioritizing self-care and incorporating regular exercise can help individuals achieve a better sense of balance in their dopamine levels. 

This improves moods, productivity, and an improved ability to handle stress. Second, we can adapt to these ingrained automatic behaviors by limiting external triggers. This technique is rooted in Cognitive-Behavioral Therapy (CBT), known as “stimulus control.”

Sepah explains that this can be achieved by doing the following:

• Moving the stimulus, like your smartphone, further away makes it difficult to access.
• Participate in a different activity that contradicts the trigger, like going for a vigorous run if you are trying to manage stress eating. 
• Utilizing software that blocks website access or relies on social accountability to avoid bypassing restrictions.

Another CBT technique, “exposure and response prevention,” can help expose us to the negative emotions that serve as internal stimuli and, over time, weaken the cycle of classical conditioning (habituation) and help restore behavioral flexibility.

Criticisms and Limitations

It’s important to note that the concept of dopamine detox is not without criticism. Some experts argue that it oversimplifies the complex role of dopamine in the brain and that complete abstinence from pleasurable activities isn’t necessary or even beneficial for most people.

Moreover, for individuals with clinical depression or other mental health conditions characterized by low dopamine activity, reducing rewarding activities could potentially be harmful.

Evidence-Based Strategies

If someone is researching ‘dopamine detox,’ it likely means they have experienced the harmful effects of our highly stimulating society. They may feel overwhelmed, addicted, or unsatisfied with everyday activities. Instead of focusing on a detox, exploring well-researched techniques that improve mental well-being, such as holistic-based strategies, psychiatric medications, and cutting-edge treatments, such as transcranial magnetic stimulation therapy (TMS), may be more beneficial. Let’s review these in a little more detail.

While often individuals may require other treatment options, or a combination of options, holistic-based strategies, play an essential role in improving mental health and are generally easy to incorporate into everyday life, including the following:

Exercise

One effective strategy for improving mental health is regular exercise. After physical activity, exercise lowers the levels of two stress hormones, cortisol, and epinephrine. Regular exercise can reduce stress, increase energy levels, and improve memory and overall mental health.

Diet

Healthy diets rich in omega-3 fatty acids (in foods like fish, chia seeds, and walnuts), B vitamins (found in eggs, legumes, and whole grains), and magnesium can boost dopamine production and improve mood. There is also evidence that a diet rich in tyrosine (in foods like poultry, dairy, avocados, bananas, pumpkin, sesame seeds, and soy) increases dopamine levels and may improve memory and mental performance.

Prioritizing Self-Care

Another essential aspect of mental health is practicing self-care and prioritizing well-being. Engaging in activities that bring you joy, such as spending time with loved ones, practicing hobbies, and engaging in self-care rituals, can help boost dopamine levels and reduce stress. Additionally, getting enough sleep, managing stress, and seeking professional help when needed are all strategies that can contribute to improved mental health.

Psychiatric Medications

In some cases, psychiatric medications prescribed by a qualified healthcare professional may be necessary to manage mental health conditions if excessive or low levels of dopamine cause depression and/or anxiety. These medications can regulate neurotransmitter levels and alleviate symptoms. 

• Antidepressants: There are several different types of antidepressants, but two of the most commonly prescribed classes are Selective Serotonin Reuptake Inhibitors (SSRIs) and Serotonin Norepinephrine Reuptake Inhibitors (SNRIs).
• Antianxiety medications: SSRIs and SNRIs are also commonly used to treat anxiety, but several other types of anxiety medications may be used, such as benzodiazepines and beta-blockers.
• Antipsychotic medications: Antipsychotics, such as typical and atypical antipsychotics, treat psychotic disorders like schizophrenia and bipolar disorder. They can lessen or alleviate symptoms such as hallucinations, delusions, and disorganized thinking. Antipsychotic medications can also be used to treat depression. 
• Mood stabilizers: Mood stabilizer medications are used to manage mood swings and stabilize mood in conditions like bipolar disorder. Lithium is a commonly prescribed mood stabilizer, but other options exist, such as anticonvulsant medications.
• Stimulants: Stimulant medications are typically prescribed to treat attention-deficit/hyperactivity disorder (ADHD) and narcolepsy. They can increase focus, attention, and alertness. Examples of stimulant medications include methylphenidate and amphetamines.
• NMDA Antagonists: Spravato is a nasal spray medication that contains esketamine, a derivative of ketamine. It has been approved for treating treatment-resistant depression and can provide rapid relief for some individuals. Ketamine has been shown to strengthen the connection between two regions of the brain involved in producing and controlling dopamine.

Transcranial Magnetic Stimulation (TMS) Therapy

Transcranial Magnetic Stimulation (TMS) therapy offers a promising approach for individuals seeking to regulate their dopamine system without relying on traditional “dopamine detox” methods. This non-invasive procedure uses magnetic fields to stimulate specific areas of the brain, including regions involved in dopamine production and regulation.

While primarily FDA-approved for treating depression and other mental health conditions, TMS has shown promise in addressing dopamine-related issues such as addiction and impulsive behaviors. By modulating neural activity in the prefrontal cortex and other key areas, TMS may help restore balance to the brain’s reward system, potentially reducing the overstimulation that leads many to seek “dopamine detoxes.”

Some studies suggest that TMS can influence dopamine release and receptor sensitivity, offering a more direct approach to managing dopamine levels than behavioral interventions alone. For individuals struggling with dopamine-driven behaviors or those who find traditional detox methods challenging, TMS therapy could provide a valuable alternative or complement to other treatment approaches. As research in this area continues to evolve, TMS may become an increasingly important tool in addressing the dopamine imbalances that underlie various mental health and behavioral issues.

Psychotherapy

Psychotherapy, or talk therapy, offers a valuable approach to addressing dopamine-related issues and developing healthier habits. While not directly altering dopamine levels, psychotherapy can help individuals understand and manage behaviors influenced by dopamine, such as addictive tendencies or impulsive actions. Cognitive Behavioral Therapy (CBT), in particular, aligns well with the principles behind “dopamine detox” by helping individuals identify trigger behaviors, develop coping strategies, and create new, healthier habits. Other forms of therapy, like Dialectical Behavior Therapy (DBT) and Mindfulness-Based Cognitive Therapy (MBCT), can aid in emotional regulation and stress management, indirectly influencing dopamine-driven behaviors. By working with a trained therapist, individuals can gain insights into their thought patterns and behaviors, learn techniques to manage cravings or compulsions and develop a more balanced relationship with dopamine-triggering activities. This approach complements other strategies mentioned earlier, providing a comprehensive toolkit for maintaining mental well-being and achieving a healthier dopamine balance.

Conclusion

It’s important to note that these techniques should be approached in consultation with mental health professionals. They can develop comprehensive strategies and provide personalized guidance to improve psychological well-being. While a dopamine detox may not be supported by scientific evidence, exploring evidence-based techniques can help individuals feel better and improve their overall mental health.

Contact Neuro Wellness Spa today and embark on a journey of personalized care and transformative treatment options for enhancing your mental health and overall well-being. Our committed team is ready to help guide you toward psychiatry, medication management, psychotherapy, TMS therapy, or other strategies aimed at your individual needs and treatment goals. Take the first step towards a healthier mind and happier life. Reach out now to schedule a consultation and start your wellness journey.

References:

1. American Psychological Association. (2020, March 4). Working out boosts brain health. https://www.apa.org/topics/exercise-fitness/stress
2. Bozzatello, P., Brignolo, E., De Grandi, E., & Bellino, S. (2016). Supplementation with Omega-3 Fatty Acids in Psychiatric Disorders: A Review of Literature Data. Journal of clinical medicine, 5(8), 67. https://doi.org/10.3390/jcm5080067
3. Costa, K. M., & Schoenbaum, G. (2022). Dopamine. Current biology: CB, 32(15), R817–R824. https://doi.org/10.1016/j.cub.2022.06.060
4. Dopamine. Cleveland Clinic. https://my.clevelandclinic.org/health/articles/22581-dopamine
5. Fei YY, Johnson PA, Omran N, Mardon A, Johnson JC. Maladaptive or misunderstood? Dopamine fasting as a potential intervention for behavioral addiction. Lifestyle Medicine. 2021. doi: 10.1002/lim2.54
6. Giles, G. E., Mahoney, C. R., & Kanarek, R. B. (2013). Omega-3 fatty acids influence mood in healthy and depressed individuals. Nutrition reviews, 71(11), 727–741. https://doi.org/10.1111/nure.12066
7. Grinspoon, P. Dopamine fasting: Misunderstanding science spawns a maladaptive fad. (2020). Harvard Medical School. https://www.health.harvard.edu/blog/dopamine-fasting-misunderstanding-science-spawns-a-maladaptive-fad-2020022618917
8. Kühn, S., Düzel, S., Colzato, L., Norman, K., Gallinat, J., Brandmaier, A. M., Lindenberger, U., & Widaman, K. F. (2019). Food for thought: association between dietary tyrosine and cognitive performance in younger and older adults. Psychological research, 83(6), 1097–1106. https://doi.org/10.1007/s00426-017-0957-4
9. Marcus, D. J., & Bruchas, M. R. (2021). Where ketamine and dopamine collide. eLife, 10, e70148. https://doi.org/10.7554/eLife.70148
10. (n.d). Mental Health Medications. National Institute of Mental Health. https://www.nimh.nih.gov/health/topics/mental-health-medications
11. Sepah, C., MD (n.d.). The Definitive Guide to Dopamine Fasting 2.0 – The Hot Silicon Valley Trend. LinkedIn. https://www.linkedin.com/pulse/dopamine-fasting-new-silicon-valley-trend-dr-cameron-sepah/
12. Sheffler ZM, Patel P, Abdijadid S. Antidepressants. [Updated 2023 May 26]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK538182/
13. Watson, S. Harvard Health Publishing. (2021, July 20). Dopamine: The pathway to pleasure. https://www.health.harvard.edu/mind-and-mood/dopamine-the-pathway-to-pleasure