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TMS for Bipolar Disorder: How It Works

Bipolar disorder is a mental illness that affects a person’s mood and can cause episodes of depression, mania, or both. While conventional treatments such as medication and psychotherapy are often used to manage bipolar disorder, many people are now turning to an alternative treatment option known as Transcranial Magnetic Stimulation (TMS) therapy. While Transcranial Magnetic Stimulation (TMS) offers promise in treating bipolar depression, understanding its specific role and limitations within a comprehensive treatment plan is crucial for patient safety and success.

Understanding Bipolar Disorder’s Complex Nature

Bipolar disorder presents unique treatment challenges due to its cyclical nature, and as such, there is no cure, but the symptoms are treatable. The condition alternates between depressive episodes and manic or hypomanic states, each requiring different therapeutic approaches. The depressive phase often proves particularly resistant to traditional treatments, leading many patients and clinicians to explore alternative options like TMS.

The four classifications of bipolar disorder each present distinct challenges:

Bipolar I manifests with severe manic episodes lasting at least seven days, often requiring immediate hospitalization. These episodes typically alternate with major depressive periods that can persist for two weeks or longer.

Bipolar II features less severe hypomanic episodes but includes major depressive periods that can significantly impair daily functioning. While less acute than Bipolar I, this form often results in chronic impairment.

Cyclothymia presents as a milder yet persistent form, with mood fluctuations occurring over two years or more. Though less severe, its chronic nature can substantially impact quality of life.

Rapid-cycling bipolar disorder involves four or more episodes within a year, creating particular treatment challenges and requiring careful monitoring of any intervention.

Our psychiatrists offer evidence-based mental health treatments and the latest psychiatric medication options through convenient online visits across California or in-person at our locations in the Los Angeles area. Schedule your appointment today.

Signs and Symptoms of Bipolar Disorder

The signs and symptoms experienced depend on whether one is having a manic episode or a depression episode. A person will usually experience 3 or more symptoms during a specific episode.

Mania Symptoms

  • Extreme Energy
  • Euphoria
  • Impulsive Decision Making
  • Engaging in Risky Behaviors
  • Extremely Talkative
  • Sleeping Very Little
  • Overly Confident
  • Constantly Active

Depression Symptoms

  • Excessive Sleeping
  • Suicidal Thoughts
  • Changes in Eating Habits 
  • No Energy
  • Feeling Worthless
  • Isolation
  • Feeling Irritable
  • No Enjoyment in Hobbies and Activities
  • Refusing to Make Decisions or Being Indecisive

The Role of TMS in Bipolar Depression Treatment

Conventionally bipolar disorder is managed by a cocktail of drug therapies, including antidepressants and mood-stabilizing medications. However, there is an ongoing clinical debate regarding the effectiveness of these treatments. Recent studies suggest that antidepressant medications may even exacerbate the intensity and frequency of manic episodes. This is not to mention the potential side effects caused by these drugs, including nausea, fatigue, weight gain, cognitive impairment, and sexual dysfunction.

By contrast, TMS offers a safe and non-invasive alternative treatment that can be used to replace or augment conventional drug therapies. TMS specifically targets bipolar depression through focused magnetic stimulation of the left dorsolateral prefrontal cortex, an area often showing reduced activity during depressive episodes. This non-invasive approach uses precisely calibrated magnetic pulses to activate neural circuits involved in mood regulation. While TMS therapy for Bipolar Disorder is only part way through the long regulatory process of getting FDA-approval, the treatment has been demonstrated to be effective both in a clinical setting and in placebo-controlled studies. For example, a recent double-blinded Brainsway study achieved a 70% response rate. Neuro Wellness Spa is proud to report an average TMS response rate of 74% after 150,000+ TMS sessions.

Important Safety Considerations

While TMS shows promise for bipolar depression, several crucial safety considerations exist:

TMS should only be administered alongside mood-stabilizing medications. This combination helps prevent potential manic episodes that could be triggered by the stimulation. Your psychiatrist will carefully monitor your medication regimen throughout TMS treatment.

Regular mood tracking becomes essential during treatment. Patients must report any symptoms suggesting hypomania or mania, including decreased sleep needs, increased energy, or racing thoughts.

Treatment protocols for bipolar disorder differ from those used for unipolar depression, often requiring modified stimulation parameters and careful timing of sessions.

Treatment Effectiveness and Clinical Research

Clinical studies demonstrate TMS’s effectiveness specifically for bipolar depression. Recent research shows response rates around 70% when combined with mood stabilizers, with Neuro Wellness Spa reporting similar success rates across more than 150,000 sessions.

TMS treatment typically begins showing results within two weeks (8-10 sessions), significantly faster than traditional antidepressant medications. However, individual responses vary, and some patients may require longer treatment courses.

The TMS Treatment Process for Bipolar Disorder

At Neuro Wellness Spa, TMS treatment follows a carefully structured protocol:

Initial Consultation: Our psychiatric team conducts a thorough evaluation of your bipolar disorder history, current medications, and treatment goals. This assessment helps determine if TMS is appropriate and how to optimize it within your treatment plan.

Treatment Setup: The first session involves precise mapping of your brain to identify the optimal stimulation location. This ensures consistent targeting throughout your treatment course.

Daily Sessions: Each 20-minute session delivers carefully calibrated magnetic pulses while you remain awake and alert. Unlike electroconvulsive therapy (ECT), TMS requires no sedation and allows immediate return to daily activities.

Ongoing Monitoring: Throughout treatment, our team carefully tracks mood symptoms and adjusts protocols as needed. This includes regular assessment for any signs of mood elevation or instability.

Medication Management and TMS

The relationship between TMS and psychiatric medications is crucial for bipolar disorder treatment. Most patients continue taking prescribed mood stabilizers throughout TMS therapy. Common medications that work synergistically with TMS include:

Lithium or anticonvulsants help prevent manic episodes, while TMS addresses depressive symptoms. These medications typically continue at stable doses during treatment.

Antipsychotics may be adjusted during TMS treatment, with changes made under close psychiatric supervision.

Your Neuro Wellness Spa psychiatrist will carefully manage this medication balance, ensuring optimal treatment outcomes while minimizing risks.

Comprehensive Care Approach

Successful bipolar disorder management extends beyond TMS and medications. At Neuro Wellness Spa, we provide:

  • Regular psychiatric monitoring to track mood stability and adjust treatments as needed
  • Psychotherapy options, including specialized approaches for bipolar disorder
  • Lifestyle management guidance to support treatment effectiveness
  • Crisis intervention protocols when needed
  • Education about bipolar disorder and treatment options

Post-Treatment Care and Maintenance

After completing the initial TMS course, many patients benefit from maintenance sessions. The frequency varies by individual, with some requiring monthly sessions while others maintain stability with less frequent treatments. Ongoing medication management and psychiatric care remain essential components of long-term success.

Insurance Coverage and Accessibility

While TMS for bipolar depression is considered off-label, many insurance providers cover treatment when properly documented. Neuro Wellness Spa’s team works directly with insurance companies to maximize coverage opportunities and minimize out-of-pocket expenses.

Taking the Next Step with Neuro Wellness Spa

If you’re struggling with bipolar depression, Neuro Wellness Spa offers specialized TMS treatment within a comprehensive care framework. Our experienced team includes psychiatrists, therapists, TMS technicians, and mental health professionals who understand the complexities of bipolar disorder.

Contact us today at 877-847-3984 to schedule a consultation at one of our psychiatry clinics in Southern California. We’ll evaluate your specific situation and determine if TMS could benefit your bipolar disorder treatment plan.

Remember, successful bipolar disorder treatment requires a carefully coordinated approach. At Neuro Wellness Spa, we’re committed to providing innovative, evidence-based care while ensuring your safety and stability throughout the treatment process.

Our psychiatrists offer evidence-based mental health treatments and the latest psychiatric medication options through convenient online visits across California or in-person at our locations in the Los Angeles area. Schedule your appointment today.
*TMS is FDA-cleared for depression, migraine, Obsessive-Compulsive Disorder, cigarette cessation, anxious depression, adolescent depression, and chronic post-traumatic/surgical pain. Research indicates that TMS to also be helpful for bipolar depression, anxiety, and cognitive impairment. Other uses for TMS therapy are considered "off-label." However, there is a growing body of research indicating the potential benefits of these off-label applications for a variety of mental health conditions. Please consult with a psychiatrist to learn more about TMS and off-label uses.
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